ARALAST (also known as Alpha-1 proteinase inhibitor)

Mechanism:

Aralast is a concentrated preparation of Alpha-1 proteinase inhibitor, which is an important factor in protecting the lungs from degradation.

Indications:

Patients with congenital deficiency of Alpha-1 proteinase inhibitor and clinical manifestation of emphysema.

Contraindications:

Aralast is contraindicated in individuals with selective IgA deficiency.

Administration:

Aralast is typically administered as a weekly infusion.  The duration is determined by the pulmonologist but can range up to 10 weeks.