CYTOXAN (also known as Cyclophosphamide)

Mechanism:

Cytoxan is an alkylating agent.

Indications:

Due to various systemic side effects, Cytoxan is not a first line agent.  Physicians, however, may consider Cytoxan for off-label use in patients with severe autoimmune diseases, including Rheumatoid Arthritis and Multiple Sclerosis, who have not responded to other treatments.

Contraindications:

Patients with a urinary outflow obstruction should not be started on Cytoxan.

Administration:

The frequency and duration of treatment will be determined by the referring physician.